Nature has been provided a good source of medicinal plants for thousands of years and an impressive number of modern drugs have been isolated from those medicinal plants. Various medicinal plants have been used for years in daily life to treat diseases all over the world. The present review is, therefore, an effort to given detailed survey of the literature Dalbergia sissoo. The plant is widely growing plant at different parts of country. It is used as traditionally to cure many diseases. The present study reveals the phytochemistry and its applications in treatment of various ailments. The genus consists of 300 species among which 25 species occur in India. The plant is used for analgesic and antipyretic activity.