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Journal of Medicinal Plants Studies
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ISSN Print: 2394-0530, ISSN Online: 2320-3862, NAAS Rating: 3.53

NAAS Rating: 3.53 NEW

Journal of Medicinal Plants Studies

2015, Vol. 3, Issue 5, Part B
Antimicrobial activity of the seeds of Hyoscyamus niger L. (Henbane) on microorganisms isolated from urinary tract infections

Gorkem Dulger, Basaran Dulger

Objective: The methanol extracts obtained from the seeds of Hyoscyamus niger L. (Solanaceae) were investigated for their antimicrobial activities against the pathogens causing complicated urine tract infections. Methods: The seeds of plant were extracted with aqueous 60% methanol. The extract was screened against urinary tract pathogens (Enterococcus faecalis, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Proteus mirabilis and Candida albicans) by disc diffusion method and microdilution method. Some antibacterial and antifungal antibiotics were used as a positive reference standard to determine the sensitivity of the strains. Results: The extracts showed strong antimicrobial activity against Enterococcus faecalis, Klebsiella pneumoniae and Candida albicans with inhibition zones of 26.0, 19.0 and 16.0 mm, with MIC’s and MBC’s or MFC’s of 4.0(8.0), 32(64) and 64(128) µg/mL, respectively. Also, the extracts exhibited moderate activity against the other test microorganisms. Conclusion: Our findings support the use of Hyoscyamus niger L. in traditional medicine for the treatment against the urine tract pathogens.
Pages : 92-95 | 1052 Views | 23 Downloads
How to cite this article:
Gorkem Dulger, Basaran Dulger. Antimicrobial activity of the seeds of Hyoscyamus niger L. (Henbane) on microorganisms isolated from urinary tract infections. Journal of Medicinal Plants Studies. 2015; 3(5): 92-95.
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