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Journal of Medicinal Plants Studies
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ISSN Print: 2394-0530, ISSN Online: 2320-3862, NAAS Rating: 3.53

NAAS Rating: 3.53 NEW

Journal of Medicinal Plants Studies

2016, Vol. 4, Issue 3, Part B
Evaluation of cytotoxicity of Terminalia arjuna (Roxb.) Wight & Arn. and Moringa oleifera Lam. in root Meristem cells of Allium cepa L

Bimal Debnath, Chiranjit Paul, Amal Debnath, Debashis Saha

The bark of Terminalia arjuna and Moringa oleifera are the two popular folk medicine that have been used for the treatment of different health problem since long back. In the present investigation cytotoxic and genotoxic effect of bark extracts of both the plants in Allium cepa root meristem cells were studied. A significant cell cycle inhibition was observed in very lower concentration (0.5-10mg/ml) of the treatments. In all the tested concentration, cytotoxic effects on cell division were also observed. The mitotic abnormalities were recorded as sticky metaphase, clumped metaphases, laggard chromosome, vagrant chromosome, chromosome bridges at anaphase and at telophase. The frequency of mitotic abnormalities was found to be directly associated with the increase in the concentration of aqueous extracts of barks of tested species. The result indicate that the inappropriate doses of these herbal medicine may lead to health complications.
A- Sticky metaphase B- Clumped metaphase, C- Laggard chromosome, D- Vagrant chromosome in Anaphase, E- Anaphase Bridge, F- Bridge in telophase.
Fig.: A- Sticky metaphase B- Clumped metaphase, C- Laggard chromosome, D- Vagrant chromosome in Anaphase, E- Anaphase Bridge, F- Bridge in telophase.
Pages : 107-110 | 972 Views | 34 Downloads
How to cite this article:
Bimal Debnath, Chiranjit Paul, Amal Debnath, Debashis Saha. Evaluation of cytotoxicity of Terminalia arjuna (Roxb.) Wight & Arn. and Moringa oleifera Lam. in root Meristem cells of Allium cepa L. 2016; 4(3): 107-110.
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