Contact: +91-9711224068
Journal of Medicinal Plants Studies
  • Printed Journal
  • Indexed Journal
  • Refereed Journal
  • Peer Reviewed Journal

ISSN Print: 2394-0530, ISSN Online: 2320-3862, NAAS Rating: 3.53

NAAS Rating: 3.53 NEW

Journal of Medicinal Plants Studies

2016, Vol. 4, Issue 4, Part D
Pleiotropic activity of Hypericum perforatum L.

Kotsiou A, Seferos N, Michael Hudu and Tesseromatis C

Hypericum perforatum L. (St John's wort) is a medicinal plant since Hippocrates era, due to its anti-inflammatory and wound/burn healing properties. Its main constituents are flavonoid aglycones (quercetin, luteolin, kaempferol), biflavonoids (apigenin, skeleton) and glycosides (hyperoside, hypericin, hyperforin isoquercitrin and quercitrin).
In addition to its wound healing properties, Hp extract reversed the arthritic symptoms in experimental Freunds adjuvant arthritis presenting its antiinflammatoty effect.
Hypericum perforatum extract exerts antidepressive and antiatherogenic activity. Furthermore it posseses oestrogen-mimetic activity, as it has been shown in a model of forced intensive swimming stress where Hp administration increased bone mass density. Moreover lipid parameters were beneficially modified under Hp in the same experimental model of stress.
Studies showed that Hp LI 160 treatment has a beneficial effect on most menopausal symptoms and potentially prevents obesity in a menopause experimental model in rats, where Hp treatment compared to estradiol administration seems to have similar activity.
Pages : 256-258 | 946 Views | 29 Downloads
How to cite this article:
Kotsiou A, Seferos N, Michael Hudu and Tesseromatis C. Pleiotropic activity of Hypericum perforatum L.. Journal of Medicinal Plants Studies. 2016; 4(4): 256-258.
Call for book chapter
Journal of Medicinal Plants Studies
Journals List Click Here Research Journals Research Journals
Please use another browser.