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Journal of Medicinal Plants Studies
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ISSN Print: 2394-0530, ISSN Online: 2320-3862, NAAS Rating: 3.53

NAAS Rating: 3.53 NEW

Journal of Medicinal Plants Studies

2017, Vol. 5, Issue 3, Part E
Cardioprotective activity of Euphorbia hirta in Isoproterenol induced Myocardial Infarction in Rats

Anandhi, Doss VA and Sowndarya R

Myocardial infarction is a major public health concern and the leading cause of death throughout the World. Considering the creditable medicinal benefits of Euphorbia hirta, the present study aimed to elucidate the cardioprotective effects of E. hirta leaf extract on isoproterenol induced myocardial infarction in rats. Prior administration of hydroethanolic leaf extract at 250 mg/kg of body weight was found to diminish the effect of isoproterenol on the levels of Total cholesterol, Triglycerides and LDL with a parallel rise in the level of HDL. The extract effect was compared with standard drug propranolol which also offered similar protection and it was further confirmed by histological changes of the heart. Thus our present study clearly indicated a significant cardioprotective activity of leaf extract due to the presence of phytochemicals and antioxidant properties.
Pages : 335-337 | 447 Views | 35 Downloads
How to cite this article:
Anandhi, Doss VA and Sowndarya R. Cardioprotective activity of Euphorbia hirta in Isoproterenol induced Myocardial Infarction in Rats. Journal of Medicinal Plants Studies. 2017; 5(3): 335-337.
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