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Journal of Medicinal Plants Studies
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ISSN Print: 2394-0530, ISSN Online: 2320-3862, NAAS Rating: 3.53

NAAS Rating: 3.53 NEW

Journal of Medicinal Plants Studies

2017, Vol. 5, Issue 5, Part D
Effects of subchronic administration of Setaria megaphylla (Steud) T. Dur and Sphinz (Poaceae) root extract on histopathological indices of rats

John Akpan Udobang and Jude Efiom Okokon

Background: Setaria megaphylla (Steud) T. Dur and Schinz (Poaceae), is a medicinal plant used routinely by the indigenes of Nigeria’s Niger Delta to treat malaria, hemorrhoids, urethritis, inflammation, diabetes, fevers and various pains (Udobang, Okokon and Etuk, 2016) [1]. The locals use this plant treat various ailments, so it becomes necessary to investigate the effect of Setaria megaphylla ethanol extract on various organs in the body
Objectives: This work was therefore designed to investigate the effect of Setaria megaphylla root extract on histopathological indices of rats during sub chronic administration.
Methodology: Setaria megaphylla ethanol root extract (150, 300, 450 mg/kg) was investigated for histopathological effects in rats organs using standard procedures.
Results: There was non-significant reductions in the weight of rats and organs and negligible and non-significant toxic effect on the organs analysed.
Conclusions: The findings of this study revealed that S. megaphylla ethanol root extract exhibited negligible toxic issue effects.
Pages : 256-265 | 615 Views | 17 Downloads
How to cite this article:
John Akpan Udobang and Jude Efiom Okokon. Effects of subchronic administration of Setaria megaphylla (Steud) T. Dur and Sphinz (Poaceae) root extract on histopathological indices of rats. Journal of Medicinal Plants Studies. 2017; 5(5): 256-265.
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