Contact: +91-9711224068
Journal of Medicinal Plants Studies
  • Printed Journal
  • Indexed Journal
  • Refereed Journal
  • Peer Reviewed Journal

ISSN Print: 2394-0530, ISSN Online: 2320-3862, NAAS Rating: 3.53

NAAS Rating: 3.53 NEW

Journal of Medicinal Plants Studies

2018, Vol. 6, Issue 6, Part C
Antinociceptive activity evaluation of leaves of Malva verticillata L.

Farhana Akter and Mohammed Rahmatullah

In acetic acid-induced writhing tests in mice, methanol extract of leaves of Malva verticillata (MEMV) dose-dependently and significantly reduced the number of writhings induced by intraperitoneal administration of acetic acid. At doses of 50, 100, 200 and 400 mg per kg body weight MEMV reduced the number of writhings by 24.1, 27.6, 34.5, and 41.4%, respectively. By comparison, a standard antinociceptive drug aspirin reduced the number of writhings by 24.1 and 51.7% respectively, when administered at doses of 200 and 400 mg per kg body weight. The results suggest that MEMV possess considerable antinociceptive activity and can possibly be used as substitute for aspirin. Preliminary phytochemical analysis showed the presence of alkaloids and flavonoids in MEMV, which classes of compounds may be responsible for the observed antinociceptive effects.
Pages : 152-154 | 94 Views | 9 Downloads
How to cite this article:
Farhana Akter and Mohammed Rahmatullah. Antinociceptive activity evaluation of leaves of Malva verticillata L.. 2018; 6(6): 152-154.
Call for book chapter
Journals List Click Here Research Journals Research Journals
Please use another browser.