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Journal of Medicinal Plants Studies
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ISSN Print: 2394-0530, ISSN Online: 2320-3862, NAAS Rating: 3.53

NAAS Rating: 3.53 NEW

Journal of Medicinal Plants Studies

2019, Vol. 7, Issue 2, Part C
Bacterial isolates from surgical wound infection and their susceptibility reaction to Cnidoscolus aconitifolius leaf extract and honey

Hanson Ige Ogbu and Emeka Claudius Igboanusi

The management of surgical wound infections has no doubt become more challenging due to widespread resistance to available antibiotics and a greater incidence of infections caused by notable bacterial strains. This therefore demands that a renewed effort be made to select suitable antimicrobial therapy from plant derived substances that will aid in the prompt healing of infected surgical wounds. In the present study antimicrobial activity of Cnidoscolus aconitifolius leaf and honey are investigated against Pseudomonas aeruginosa, Pseudomonas fluorescence, Staphylococcus aureus and Escherichia coli. These isolates were obtained from the wound laboratory, microbiology department, University of Port Harcourt Teaching Hospital, Nigeria. C. aconitifolius extract was prepared using methanol and water as extraction solvents. The samples were subjected to phytochemical and antimicrobial examinations using standard methods. Results of phytochemical analysis indicated the presence of alkaloids, saponins, tannins, flavonoids, carbohydrates and steroids. Antimicrobial effects of C. aconitifolius leaf extract, honey, extract/honey combination was in decreasing order: P. fluorescence > P. aeruginosa > S. aureus > E. coli. The variable sensitivity to leaf extract, honey, extract/honey combination seems to relate to the different resistance levels between the microbial species. The susceptibility test carried out using commercial antibiotics shows P. fluorescence and P. aeruginosa as the most susceptible, while E. coli was least susceptible. This may be due to their differences in cell wall composition, metabolism, nature, resistance to antibiotics or local environmental factors. The study highlights the role of natural product in broadening antimicrobial effectiveness against drug resistant organisms.
Pages : 163-170 | 349 Views | 15 Downloads
How to cite this article:
Hanson Ige Ogbu and Emeka Claudius Igboanusi. Bacterial isolates from surgical wound infection and their susceptibility reaction to Cnidoscolus aconitifolius leaf extract and honey. Journal of Medicinal Plants Studies. 2019; 7(2): 163-170.
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