The main objective of the present work is to find out good pharmacological activities in herbal source with theirrnpreliminary phytochemical study, and also it is aimed to investigate of ethanol and aqueous extracts of dried stem ofrnplant ‘Kalanchoe pinnata(lam.)Pers.’ against with Anti-inflammatory and in rats and Analgesic activity inrnmice.Normally herbal products are free from side effects/adverse effects and they are low cost medicines, which willrnbe beneficial for human being. The main objective of this work is to develop potent Anti-hyperglycemic, Antiinflammatory,rnanalgesic, having no or minimum side effects from indigenous plants for the therapeutic management.