2016, Vol. 4, Issue 3, Part B

author(s)
Ved Prakash, Shelly Rana, Anand Sagar

abstract
The antibacterial activity of the methanolic and acetone leaf extracts of V. thapsus was determined in-vitro against medically important pathogens such as Escherichia coli, Yersinia pestis, Bacillus cereus, Pseudomonas aeruginosa, Listeria monocytogenes and Staphylococcus aureus following agar-well diffusion method using different concentrations (25%, 50%, 75% and 100%). Results showed low to significant antibacterial activity against the mentioned bacterial strains. Methanolic leaf extract was found to be more effective against selected pathogenic bacterial spp. as compared to acetone leaf extract. Further the leaf extract of both plants inhibited gram- positive bacteria more efficiently than gram- negative bacteria. Therefore, the leaf extracts of these plants can be selected for further investigation to determine their therapeutic potential