Phytochemicals are responsible for medicinal activity of plant species. They have ability for curing various ailment and possesses potential anti-inflammatory, anti-bacterial, anti-oxidant and anti-fungal properties. Natural products from medicinal plants, either as pure compounds or as extracted out, provide opportunities for new drug leads because of the unmatched availability of chemical diversity. Due to raising demand for chemical diversity nowadays in screening programs, seeking therapeutic drugs from herbal products, these are quite interesting throughout the world. Botanicals and herbal preparations for medicinal purpose contain various types of bioactive compounds. Colocasia esculenta commonly known as taro belonging to family Araceae are herbaceous perennial plants with a large corm on or just below the ground surface. Continuous research have revealed many chemical constituents isolated from this plant to exhibit several biological activities such as antimicrobial activity, fever, anti-inflammatory, stomach disorder, conjunctivitis, and loss of appetite for children. The present study aims at studying the anti urolithiatic activity of methanolic and chloroform extracts of the leaves of Colocasia esculenta using artificial kidney membrane. From the above study, it was found that it does show the urolithiatic study.