Wound healing potential of the crude leaf extract of Stachytarpheta Jamaicensis Linn. Vahl (Kandikandilaan) on inducedwounds in rats
Emiliana Dela Cruz Caluya
The wound healing activity of the ethanolic crude leaf extract of Stachytarpheta jamaicensis was evaluated in albino rats by excision wound model for a period of 20 days. In this study, the rats were divided into four groups with 9 replicates; T1, the control group where no treatment was given to the animals, T2 for animals treated with commercial 10% povidone- iodine, T3 for animals treated with 95% ethyl alcohol and T4 for animals treated with the crude extract of S. jamaicensis. Wound healing was monitored on day 4, 8, 12 and 16. Scabs collected on day 4 and 8 were subjected to Biuret Test and protein content was indicated by the intensity of blue color. External application of the crude leaf extract of S. jamaicensis significantly accelerates wound healing in albino rats. Phytochemical investigations on the crude leaf extract of S. jamaicensis revealed the presence of phytoconstituents such as tannin, flavonoids, saponin, terpenoids, glycosides, phenols which exhibit wound healing potential.