In vivo anti-inflammatory activity of the endemic medicinal plant Caralluma sarkariae R.Br. using Carrageenan induced paw oedema in swiss albino mice
Dr. U Danya
Caralluma sarkariae is a succulent, endangered and endemic plant from southern Western Ghats. This species has used by ethanomedicinal practices by traditional healers of Southern Tamilnadu. Traditionally the plant has been used as the treatment of Rheumatism, ulcer, asthma, fever, inflammation, diabetes, stress, cancer and obesity. The methanolic extract of C. sarkariae was investigated for anti-inflammatory activity by carrageenan induced paw oedema method. The result indicated that the methanolic extract at the dose of 150mg/kg b.wt showed a maximum anti-inflammatory activity at 69% as compared to the standard drug. The findings of the study suggest that the methanolic extract of C. sarkariae showed significant activities which confirm the traditional usage of this medicinal plant to treat the inflammatory diseases.