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P-ISSN: 2394-0530, E-ISSN: 2320-3862
2017, Vol. 5, Issue 5, Part D
Effects of subchronic administration of Setaria megaphylla (Steud) T. Dur and Sphinz (Poaceae) root extract on histopathological indices of rats
John Akpan Udobang and Jude Efiom Okokon
Background: Setaria megaphylla (Steud) T. Dur and Schinz (Poaceae), is a medicinal plant used routinely by the indigenes of Nigeria’s Niger Delta to treat malaria, hemorrhoids, urethritis, inflammation, diabetes, fevers and various pains (Udobang, Okokon and Etuk, 2016) [1]. The locals use this plant treat various ailments, so it becomes necessary to investigate the effect of Setaria megaphylla ethanol extract on various organs in the body
Objectives: This work was therefore designed to investigate the effect of Setaria megaphylla root extract on histopathological indices of rats during sub chronic administration.
Methodology: Setaria megaphylla ethanol root extract (150, 300, 450 mg/kg) was investigated for histopathological effects in rats organs using standard procedures.
Results: There was non-significant reductions in the weight of rats and organs and negligible and non-significant toxic effect on the organs analysed.
Conclusions: The findings of this study revealed that S. megaphylla ethanol root extract exhibited negligible toxic issue effects.
Pages : 256-265 | 1503 Views | 127 Downloads
How to cite this article:
John Akpan Udobang, Jude Efiom Okokon. Effects of subchronic administration of Setaria megaphylla (Steud) T. Dur and Sphinz (Poaceae) root extract on histopathological indices of rats. J Med Plants Stud 2017;5(5):256-265.
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