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P-ISSN: 2394-0530, E-ISSN: 2320-3862
2017, Vol. 5, Issue 6, Part B
Hematological and biochemical indices on subchronic administration of Setaria megaphylla (Steud) T. Dur and sphinx (Poaceae) root extract on rats
John Akpan Udobang and Jude Efiom Okokon
Background: Setaria megaphylla (Steud) T. Dur and Schinz (Poaceae), is a medicinal plant popularly used South-South Nigeria to treat malaria, hemorrhoids, urethritis, inflammation, diabetes, fevers and various pains(Udobang, Okokon and Etuk, 2016) [1]. The persistent and consistent use of Setaria megaphylla by the locals to treat various ailments therefore necessitated this investigation of its effects on blood.
Objectives: This work was therefore designed to investigate the effects of Setaria megaphylla ethanol root extract on hematological and biochemical parameters during sub chronic toxicity administration.
Methodology: The effects of Setaria megaphylla ethanol root extract (150, 300, 450 mg/kg) on hematological and biochemical indices (liver and kidney functions) in rats were investigated for using standard procedures.
Results: There was non-significant effects on the hematological and biochemical parameters during sub chronic toxicity investigation.
Conclusions: The findings of this study revealed that S. megaphylla ethanol root extract exhibited negligible toxic effects.
Pages : 81-85 | 1464 Views | 116 Downloads
How to cite this article:
John Akpan Udobang, Jude Efiom Okokon. Hematological and biochemical indices on subchronic administration of Setaria megaphylla (Steud) T. Dur and sphinx (Poaceae) root extract on rats. J Med Plants Stud 2017;5(6):81-85.
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