In-vitro investigation of antioxidant activity and phytochemical screening of Persicaria glabra
Utsha Chakma, Zarif Morshed, Md. Nasiful Islam, Tushar Ahmed Shishir, Maliha Tasnim Deeba, Kazi Nuruddin Al Masud and Rezowana Islam
This study was conducted to evaluate the antioxidant property and perform the phytochemical screening of Persicaria glabra. The plant belongs to the Polygonaceae family and locally used analgesic agent. This study provides a scientific basis for the use of Persicaria glabra in traditional medicine. The whole plant was extracted using methanol. The extract was subjected to antioxidant activity determination and phytochemical screening. The phytochemical screening of Persicaria glabra showed the presence of alkaloids, flavonoids, glycosides, phenol, phlobatannin, resins, sterol and tannins but showed absence of tannin, resin and quinone. The total phenolic content of the methanolic extract of the leaves of Persicaria glabra was found to be 106.877 (mg of GAE / gm of extractives). Methanolic extract solution presented notable free radical scavenging activity with an IC50 value of 5.524μg/ml which is comparable with the value of standard Ascorbic Acid, which provided an IC50 value of 3.01µg/ml.
Utsha Chakma, Zarif Morshed, Md. Nasiful Islam, Tushar Ahmed Shishir, Maliha Tasnim Deeba, Kazi Nuruddin Al Masud, Rezowana Islam. In-vitro investigation of antioxidant activity and phytochemical screening of Persicaria glabra . J Med Plants Stud 2018;6(2):237-242.