GC-MS analysis and antimicrobial activity of alkaloids of Tecomella undulata
Tecomella undulata (Sm.) Seem is a monotypic genus belonging to family Bignoniaceae. The plant holds tremendous potential of medicinal value and has been traditionally used in various ailments like syphilis, leukoderma, blood disorders to name a few. The plant has gained prominence due to presence of some prominent secondary metabolites. The present study focuses on the GC-MS analysis of extracts of all the plant parts of T. undulata which revealed the presence of certain bioactive compounds like stigmasterol, sitosterol, thiazoline, phytol, pthalic acid, methyl alpha ketopalmitate and so forth. A total of about 20 bioactive compounds were identified. Antimicrobial activity of the extracts was assayed against pathogenic bacteria and fungi. The alkaloids from leaf extracts showed antimicrobial activity against E. coli and B. subtilis. The study thus infers that the presence of bioactive components may be the principle behind the antimicrobial property of different plant parts and therefore Tecomella forms a potential plant for herbal drug formulation.