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Journal of Medicinal Plants Studies
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ISSN Print: 2394-0530, ISSN Online: 2320-3862, NAAS Rating: 3.53

NAAS Rating: 3.53 NEW

Journal of Medicinal Plants Studies

2018, Vol. 6, Issue 6, Part B
Docking study of selected Vitis vinifera seeds constituents on dengue viral proteins: An in silico approach

M Bhavya, M Ramya, N Nagarjun, Nagarathna Amresh and Balasubramanian Sathyamurthy

Dengue is a mosquito-borne systemic viral infection caused by any of the four antigenically related dengue viruses (DENV).The dengue virus belongs to the Flaviviridae family of viruses that cause diseases in humans.A virtual screening analysis of phytochemical structures with dengue virus protein targets has been carried out using a molecular docking approach with Vins vinifera seeds. Grapes (Vitis vinifera) are believed to have health benefits due to their antioxidant activity and polyphenols. In this study we examined the binding affinities of 14 ligands with seven non structural Dengu viral proteins through In Silico methods like virtual screening and docking process which showed that compound F and compound N had high binding efficiencies with these proteins along with the type of hydrogen bonds and their respective amino acid residues at their docked sites.
Pages : 100-105 | 496 Views | 28 Downloads
How to cite this article:
M Bhavya, M Ramya, N Nagarjun, Nagarathna Amresh, Balasubramanian Sathyamurthy. Docking study of selected Vitis vinifera seeds constituents on dengue viral proteins: An in silico approach. J Med Plants Stud 2018;6(6):100-105.
Journal of Medicinal Plants Studies
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