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Journal of Medicinal Plants Studies
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ISSN Print: 2394-0530, ISSN Online: 2320-3862, NAAS Rating: 3.53

NAAS Rating: 3.53 NEW

Journal of Medicinal Plants Studies

2019, Vol. 7, Issue 1, Part B
Evaluation of biochemical markers in type 2 diabetes mellitus with adjunct therapy of fenugreek seed aqueous extract

Shubhangi M Dalvi, Mrinalini S Patwardhan, Neelam Yeram, Vinayak W Patil and Sanjeev Y Patwardhan

Background: Trigonella foenum-graecum seeds have been suggested to have potential anti-diabetic effects.
Aim: To study effects of fenugreek seeds aqueous extract on glycemic status, insulin resistance, homeostatic model assessment, safety parameters and antioxidant superoxide dismutase in Type 2 Diabetes Mellitus (T2DM) subjects and its correlation.
Methods: Randomized case-control study consisting of control (n=30), T2DM (n=30) and T2DM patients with adjunct therapy (n=30) of 1.32g fenugreek seeds aqueous extract for 3 months. Blood glucose, HbA1C, lipid profile, liver and kidney function tests were done using chemistry autoanalyzer. Insulin and C-peptide were done on chemiluminescence. Malondialdehyde and superoxide dismutase were analysed using spectrophotometer.
Results: Glucose, HbA1C and malondialdehyde were significantly lowered after 3 months in group receiving adjunct therapy. Insulin resistance, anthropometric and antioxidant status were improved while haemoglobin, alanine transaminase and renal functions remained unaltered.
Conclusion: Aqueous extract of fenugreek is effective and safe to control hyperglycemia in T2DM.
Pages : 109-113 | 404 Views | 22 Downloads
How to cite this article:
Shubhangi M Dalvi, Mrinalini S Patwardhan, Neelam Yeram, Vinayak W Patil, Sanjeev Y Patwardhan. Evaluation of biochemical markers in type 2 diabetes mellitus with adjunct therapy of fenugreek seed aqueous extract. J Med Plants Stud 2019;7(1):109-113.
Journal of Medicinal Plants Studies
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