in vitro antidiabetic potential and GC-MS analysis of Digera muricata and Amaranthy cruentus
Dr. K Ramalashmi
The present study focuses on two plants of the family Amaranthaceae, and order Caryophyllales viz., Digera muricata and Amaranthy cruentus. All the medicinal plants were biologically active and plays major role in curing various hazardous human diseases. Therefore, the present work was undertaken to explore phytochemical analysis of these samples from the leave tissues and finally after analysis these are considered as rich source of phytoconstituents. The leaves of the selected two medicinal plants were washed, air dried and then powdered. Totally five different extracts namely aqueous, methanol, ethanol, chloroform and acetone extract of leaf samples were used for the phytochemical analysis to compare the phytochemical constituents in the selected plants. The results of the phytochemical analysis of these medicinal plants showed that the alkaloid, flavanoids, glycoside, amino acids, fatty acids, carbohydrates, proteins, phenolioc, tannins, steroids, terpenoids, anthocyanins, leucoanthocyanins, coumarins and emodins were found to be present in afore mentioned medicinal plants. The GC chromatograms was also performed on methanol extract and showed the retention time in the column and detected the peaks which correspond to the bioactive compounds present in the extract. The presence of polyphenol and antioxidant constituents such as flavonoids from the selected medicinal plants showed to have the ability to reduce blood glucose levels. The present finding reveals that the methanol extract of Digera muricata effeciently reacts with alpha-amylase in an extract dependent manner than Amaranthy cruentus by in-vitro analysis. Hence, the present work was undertaken to evaluate and compare the antidiabetic potential and also to support of the traditional claims.