2020, Vol. 8, Issue 1, Part A

author(s)
Karen Morales-Vela, Flor Celeste Pérez-Sánchez, José M Padrón and Olivia Márquez-Fernández

abstract
There are many species of endemic plants from Mexico, without food or commercial use, but with different applications in traditional medicine and valuable for their content of secondary metabolites. In this sense, we found two species of Cucurbitaceae family plants natives of southeast and gulf of México, used traditionally as soap and laundry agent, control of some pests, and it has also been used as infusion for the treatment of different types of dermatitis and stomachache. In the present work, we evaluate the antiproliferative activity in vitro, of six crude organic extracts, tested against six human tumor cell lines, A549 (lung), HBL-100 (breast), HeLa (cervix), SW1573 (lung), T-47D (breast) and WiDr (colon), the results indicated that at least three extracts from both species presents an interesting antiproliferative activity against five tumor cell lines.