Hypericum perforatum for experimental skin burns treatment in rats in comparison to nitrofurazone
Kotsiou A and Tesseromatis C
Overexposure to sun, radiation, chemical or electrical contact resulting tissues damages.
The treatment of burns depends on the location and severity of the damage. Burns are characterized by degree, based on the severity of the tissue damage. Damage also may extend to the underlying fat, muscle, or bone. Hypericum perforatum L (HP - St. Johns wort) has been used widely for the treatment of burn injuries for many years in traditional medicine.
The aim of study was to investigate HP treatment in comparison to nitrofurazone in experimental thermal burns in rats.
Administration of HP four times a day within the first 24 hours is clearly effective in wound healing in the experimental thermal second degree burn modality as a plant with various biological activities such as antidepressant, wound-healing, anti-inflammatory, and antimicrobial activity against bacterial and fungal strains is significantly superior to the antimicrobial nitrofurazone treatment.