2021, Vol. 9, Issue 5, Part A

author(s)
G Shanthini Nachiar, Dr. T Purushoth Prabhu, C Kavitha and T Sheela

abstract
Chlorhexidine commonly known by its salt forms chlorhexidine gluconate or chlorhexidine acetate is a disinfectant and antiseptic which are available in many dosage forms. In recent times the emerging resistance towards the chlorhexidine and other antibiotics such as, clindamycin, gentamycin, bacitracin, polymyxin and so on. So, in this review we have assessed the methods for detection of reduced susceptibility to the following substance and the prevalence of coresistance to other antimicrobial agents. So, we selected some of the traditional way of antiseptics such as Tridax procumbens, Acalypha indica, and Aegle marmelos. The reason for choosing these species are found to have good antibacterial activities especially against E. coli, B. subtilis, S. aureus, and other streptococcus species. The work has been performed to check the antimicrobial activities of the extracted active components and then combinations of the above mentioned resistant developed antibiotic and antiseptics with the extracted active principles of the traditional antimicrobial agents and to observe the synergism and to choose the most potential extract and potential combinations among those.