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Journal of Medicinal Plants Studies
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ISSN Print: 2394-0530, ISSN Online: 2320-3862

Journal of Medicinal Plants Studies

2022, Vol. 10, Issue 2, Part A
Glucose lowering effect of wild banana cultivar of Musa acuminata L. fruit peels from Bandarban, Bangladesh in Swiss albino mice

Md. Abdus Samad Azad, Rownak Jahan and Mohammed Rahmatullah

Diabetes is a debilitating disease, which has become a serious concern in Bangladesh. Earlier studies have shown that extracts of fruit skins of various cultivars of banana species can improve glucose tolerance in glucose-loaded mice. The objective of this study was to evaluate through oral glucose tolerance test (OGTT) of methanol extract of fruit peels of a wild cultivar of Musa acuminata, which can be found in southeast Bangladesh forests. In OGTT, ripe fruit skin methanolic extract of Musa acuminata (MEMA) showed a reduction by 0.04, 19.65, 19.80 and 26.84%, when administered per kg body weight in mice at doses of 50, 100, 200 and 400 mg, respectively. A standard glucose lowering drug, glibenclamide decreased blood glucose levels by 21.08 and 37.38% at doses of 2 and 10 mg. Overall, the findings indicate that MEMA can improve glucose tolerance and may be of potential use to diabetic patients.
Pages : 30-33 | 171 Views | 9 Downloads
How to cite this article:
Md. Abdus Samad Azad, Rownak Jahan, Mohammed Rahmatullah. Glucose lowering effect of wild banana cultivar of Musa acuminata L. fruit peels from Bandarban, Bangladesh in Swiss albino mice. J Med Plants Stud 2022;10(2):30-33. DOI: 10.22271/plants.2022.v10.i2a.1387
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