2022, Vol. 10, Issue 4, Part C

author(s)
Divya Raj, Mrudula Sanjay Shah and Deoraj Sharma

abstract
A significant class of extensively present secondary metabolites in the plant kingdom with a wide range of structural variations are phenolic compounds. These substances can be found as free or matrix-bound substances, aglycones or glycosides, monomers, or as parts of highly polymerized structures. They are also not evenly distributed throughout the plant, and their stability varies greatly. This significantly complicates their extraction and isolation processes, making it impossible to recommend a single standardized procedure for all phenolics and/or plant materials. Instead, procedures must be optimized based on the nature of the sample, the target analytes, and the study's overall goal. We have attempted to summarize the main steps in the extraction, isolation, and determination of phenols from medicinal plants.