Effects of the aqueous leaf solution of Moringa oleifera on some hematological and biochemical parameters in male Wistar rats
Ojeka SO, Iyogun LD and Dr. MT Bekinbo
Moringa oleifera is a widely used medicinal herb but often in crude forms and arbitrarily. Thus, this study aimed to investigate the effects of the crude aqueous leaf solution of Moringa oleifera (ALSMO), on some haematological and biochemical parameters in male Wistar rats. Twenty (20) male Wistar rats were randomly separated into 5 groups of 5 rats each. While Group 1 served as control with no treatments, groups 2, 3 and 4 were treated with 40, 60 and 80mg/kg respectively of the ALSMO. After 28 days of treatment, analysed blood samples from the rats revealed dose-dependent significant (p<0.05) increases in blood cells in the treated animals compared to the control group. And significantly (p<0.05) reduced triglyceride and high density lipoprotein cholesterol levels in treated rats. While ALSMO may boost some haematological parameters and reduce risk of atherosclerosis, higher doses of ALSMO may result in hepato-renal toxicities in the study animals.