2023, Vol. 11, Issue 4, Part A

This review aims to critically evaluate the existing evidence derived from randomized clinical trials to determine the effectiveness of W. somnifera (ashwagandha) in enhancing male sexual health outcomes. Extensive searches were conducted in databases including PubMed, Library of Congress, JISC Library, ClinicalTrials.gov, mRCT, Google Scholar, Embase, Web of Science, CINAHL, Medline, and Cochrane. Among the initially identified 8,203 articles with potential relevance, a thorough assessment of full-text articles was performed, resulting in the inclusion of 5 studies that satisfied all predefined inclusion criteria. All included studies were evaluated as having a low risk of bias. Four of the included studies reported significant intergroup differences before and after intervention, thus providing support for the use of W. somnifera as a supplement to enhance male sexual health. However, despite these promising results obtained from clinical trials, the current evidence remains insufficient to firmly endorse the use of W. somnifera for its impact on male sexual health.