2023, Vol. 11, Issue 4, Part B

The present study of preliminary phytochemical screening and antibacterial activity was carried out in Tinospora cordifolia leaf, stem and roots extracts. Standard procedure involving cold maceration technique was conducted on the plant extracts for screening the phytochemical constituents using different polar solvents like aqueous, methanol, butanol and ethanol and a non-polar solvent like chloroform. This was followed by antibacterial activity using plant butanolic extracts by using well diffusion method since the butanolic extract of leaf, stem and root of T. cordifolia showed highest positive results for the presence of phytochemicals. Further in antibacterial activity highest zone of inhibition was shown at 80 µg/ml concentration against Escherechia coli in stem butanolic extract. Hence it became evident that T. cordifolia comprises of copious phytochemicals/secondary metabolites which possess antibacterial properties and can be used for development of novel drugs for curing infectious diseases.