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Journal of Medicinal Plants Studies
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P-ISSN: 2394-0530, E-ISSN: 2320-3862

2024, Vol. 12, Issue 1, Part A

Phytochemical screening, analgesic, anti-hyperglycemic and hepatoprotective potentials of Codariocalyx motorius (Houtt.) Leaves Extract

Neloy Kundu, Brototi Chakrabarty, Rabindra Nath Acharyya, Md. Moklesur Rahman Sarker, Md. Abdul Mazid and Md. Mustafizur Rahman

This study was performed on Codariocalyx motorius (Houtt.) leaves commonly known as telegraph plant, is a member of the Fabaceae family, to investigate the phytochemical and various pharmacological activities. Qualitative and quantitative phytochemical screenings confirmed the existence of a variety of phytochemical groups. Total phenolic, flavonoid and tannin contents were 81.24 mg gallic acid equivalence/g, 190.90 mg quercetin equivalence/g and 77.29 mg gallic acid equivalence/g, respectively in the extract. In acetic acid-induced writhing model, the extract inhibited the writhing reflex by 49.4% at a dose of 500 mg/kg body weight. In Oral glucose tolerance test, the extract reduced blood glucose levels in a dose-dependent manner in hyperglycemic mice. The extract treated mice also showed the reduction of bilirubin, SGPT, SGOT, and ALP levels in a dose-dependent manner in paracetamol induced hepatoprotective test, when the doses were given of 250 and 500 mg/kg. The outcomes of these experiments support the applications of this plant in conventional medicine.
Pages : 63-69 | 800 Views | 372 Downloads


Journal of Medicinal Plants Studies
How to cite this article:
Neloy Kundu, Brototi Chakrabarty, Rabindra Nath Acharyya, Md. Moklesur Rahman Sarker, Md. Abdul Mazid, Md. Mustafizur Rahman. Phytochemical screening, analgesic, anti-hyperglycemic and hepatoprotective potentials of Codariocalyx motorius (Houtt.) Leaves Extract. J Med Plants Stud 2024;12(1):63-69. DOI: 10.22271/plants.2024.v12.i1a.1627
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