2024, Vol. 12, Issue 1, Part B

author(s)
Jisa Ann Sabu, Brijithlal ND and Renjitha RS

abstract
In this article, we demonstrate the green synthesis of copper oxide (CuO) nanoparticle using the aqueous extract of Merremia tridentata (L.) Hallier f., which serves as a capping and reducing agent. The biosynthesized CuO nanoparticles were characterized by UV-Visible spectroscopy and X-ray diffraction (XRD). The in vitro antibacterial activity of biosynthesized nanoparticle was compared with the ethanol and ethyl acetate extracts of Merremia tridentata. The biosynthesized CuO nanoparticles shows significant inhibition activity against Bacillus subtilis (MTCC No.2413), Klebsiella pneumoniae (MTCC No.3384), Staphylococcus aureus (MTCC No.87) and Escherichia coli (MTCC No.443) with an inhibition zone of 14 mm, 13 mm, 12 mm and 11 mm respectively, when compared to the other extracts. The potent antibacterial activity of eco-friendly, plant based CuO nanoparticles from Merremia tridentata can be exploited as a remedy against the tested pathogens.