2024, Vol. 12, Issue 1, Part C

author(s)
Imtiaz Mahmud, Md. Shamsur Rahman, Asit Baron Sarker and Md. Raihan Parvez

abstract
Xylocarpus granatum Koen is traditionally used to treat fever, cholera, colic, diarrhoea and other abdominal affections. The present study aims to phytochemicl screenings and assessment of potential antioxidant and antimicrobial activities of X. granatum leaves. The DPPH free radical scavenging assay was used to quantify antioxidant activity and total content of phenolic, flavonoids, tannin was also determined. Besides, disc diffusion assay was used to evaluate antibacterial effect. Phytochemical analysis of this extract showed the existence of glycosides, tannins, protein, saponin, steroids & flavonoids. Total phenolic, flavonoid and tannin content for extract were 195.9 mg gallic acid, 555.57 mg quercetin and 122.0 mg gallic acid equivalent per gram of dry extract, respectively. In the antibacterial activity test the extract showed mild activity against Vibrio cholerae, E. coli, Staphylococcus aureus and Streptococcus pyogenes at the dose of 250 µg/disc and 500 µg/disc in comparison with Kanamycin (30 µg/disc) but was resistant to Shigella dysenteriae or Shigella flexneri.