2024, Vol. 12, Issue 1, Part C

author(s)
Idongesit Bassey Umoh, Imoh Emmanuel Ukoh, Favour Nyoh Beshel, Enene Esu Ukpai, Samuel Kelechi Mobisson, Jeremiah Etim Antai, Perowei Azosibe, Azibaobom Karibi, Ukrakpo Oghenemega Sophia and Adienbo Emmemodi Nwadighi

abstract
The human population consuming thermally-oxidized palm oil (TPO) is on the increase and there is no known remedy to it associated diseases. This study evaluates the impacts of fresh palm oil and vitamin E on lipid profiles of rat fed TPO. Sixty albino male rats were grouped into 6 (n=10). Group 2, 3, 4, 5 and 6 were fed TPO, fresh palm oil, vitamin E, TPO + fresh palm oil and TPO + vitamin E respectively. Group 1 acted as the control. 15 g of the oils was added to 85 g rat food to prepare respective diet and vitamin E 200 mg/kg/day orally. After treatment, serum analysis revealed that TPO significantly (p<0.05) alter lipid profiles negatively compared to control. But fresh palm oil and vitamin E significantly (p<0.05) reverses lipid profiles of TPO fed rats. Fresh palm oil and vitamin E may boost lipid indices and lessen the chance of cardiovascular harms.