Formulation and evaluation of Phyllanthus niruri L. leaf extract in the management of hepatotoxicity
Harshali D Khairnar, Aarti J Pawara and Purva D Sonje
Phyllanthus niruri (Phyllanthus carolinianus blanco) is commonly known as Bhumi Amla. In Ayurveda P Niruri has been extensively used, both as edible (tonic) plants and for its therapeutic potentials. This plant belongs to Euphorbiaceae family. In India it is used as a herbal medicine and called as ‘Bhumi Amla’. It is a large genus comprising about 700 species in tropical and subtropical regions. The leaves of Phyllanthus niruri collected from botanical garden. The extraction process was carried out using maceration extraction method. The leaves are extracted in ethanol solvent and evaluated for phytoconstitutes present in them. For phytochemical analysis of plant extract chemical test. The plant extract contains vitamins C, Fatty acid, decanoic acid, gallic acid, flavanoid, alkaloids, saponin, phenolic compound. The present study provides that solvent extract of Phyllanthus niruri contains medicinally important bioactive compounds and this justifies.
The use of plant species as traditional medicine for treatment of various diseases like anti inflammation antioxidants, antimicrobial agent, analgesic and antipyretic, anti-tumor and hepatoprotective, antiulcerogenic activities. The Phyllanthus niruri leaf extract aimed to investigate the protective effect management of hepatotoxicity by formulation of syrup & evaluated their parameters and efficacy and safety foranimal and human. The final and its effectiveness in managing of Hepatotoxicity.
Harshali D Khairnar, Aarti J Pawara, Purva D Sonje. Formulation and evaluation of Phyllanthus niruri L. leaf extract in the management of hepatotoxicity. J Med Plants Stud 2024;12(3):92-102.