2024, Vol. 12, Issue 4, Part A

author(s)
Anil U Chopade, Manojkumar U Chopade, Harshal S Patil and Suraj Ade

abstract
A one-pot multicomponent reaction was established for the synthesis of benzimidazole derivatives through the interaction of o-phenylenediamine and aromatic aldehydes, utilizing beetroot extract as a catalytic medium. Beetroot extract, sourced from Beta vulgaris L., exhibited noteworthy catalytic activity in the production of the target compounds. This method is characterized by mild reaction conditions, straightforward product separation, yielding moderate to high product quantities, and short reaction durations. These attributes render this approach significantly more appealing than previously reported methods for synthesizing benzimidazole derivatives.