Formulation and evaluation of polyherbal antifungal cream by using neem, guduchi and mint plant extract
Sourabh J Chougule, Seema Shinde and Nilesh Chougule
Fungal infections pose a significant challenge to public health, necessitating the development of effective and safe antifungal agents. Herbal remedies have garnered attention for their potential antimicrobial properties, including antifungal activity. In this study, we formulated a polyherbal antifungal cream utilizing the synergistic effects of neem (Tinospora cordifolia), guduchi (Tinospora cordifolia), and mint (Mentha spp.). These botanical extracts are renowned for their broad-spectrum antimicrobial activities and have been traditionally used in various medicinal preparations. The cream was prepared using a standardized method and evaluated for its antifungal efficacy against clinically relevant fungal strains using agar diffusion and broth dilution methods. Additionally, physicochemical properties such as pH, viscosity, and stability were assessed to ensure product quality and consistency. Preliminary results demonstrated promising antifungal activity of the polyherbal cream against common fungal pathogens, including Candida albicans and dermatophytes. Furthermore, the cream exhibited favorable physicochemical characteristics suitable for topical application, including a pH conducive to skin health and optimal viscosity for easy Spreadability. Overall, our findings suggest that the polyherbal antifungal cream containing neem, guduchi, and mint holds great potential as a natural alternative for the management of fungal infections. Further studies including clinical trials are warranted to validate its efficacy and safety for clinical use.
Sourabh J Chougule, Seema Shinde, Nilesh Chougule. Formulation and evaluation of polyherbal antifungal cream by using neem, guduchi and mint plant extract. J Med Plants Stud 2024;12(4):105-110.