2024, Vol. 12, Issue 4, Part D

author(s)
Shraddha Hajare, Mayuri Bhadalekar and Nilesh Chougule

abstract
This study presents the formulation and evaluation of an wound Healing Gel utilizing extract of Tridax procumbens leaves and moringa leaves. Herbal gels possess a unique property that allows for easy application and removal, making them a widely accepted and effective method for dosage control. Tridax procumbens, has been utilized in traditional Indian medicinal systems for its wound healing properties, as well as it possess Antibacterial property. The gel formulation was designed by using Carbapol 940, Tridax procumbens leaf extract, propylene glycol, methyl paraben, propyl paraben and required amount of distilled water. In the current investigation, five formulations with various carbapol concentrations as well as Moringa oleifera and Tridax extracts were created and optimised. The skin pH was maintained by drop wise addition of Tri-ethanolamine. The physicochemical parameters of formulations such as pH, spreadibility, viscosity etc. were determined. For optimised formulations in Trials 1, 2, and 3, the gel's viscosity and spreadability were appropriate. Herbal medications are considered safer than allopathic medicines as allopathic medicines due to their reduced side effects. The survival of the active moiety relies on the preparation of extracts and their formulations for better absorption and penetration into the systemic circulation. Under typical storage conditions, the preparation was stable and did not cause skin irritation.