2024, Vol. 12, Issue 4, Part D

author(s)
Aniket Desai, Abhishek Desai and Nilesh Chougule

abstract
The purpose of this study was to create and assess a polyherbal antifungal cream by combining the beneficial effects of Ajwain (Trachyspermum ammi), Tulsi (Ocimum sanctum), Cumin (Cuminum cyminum), and Neem (Azadirachta indica). Using a standardized process, extracts of these medicinal plants—known for their antifungal properties—were added to the cream's formulation. A range of physicochemical properties, including pH, viscosity, spread ability, and stability, were assessed in order to guarantee the cream's quality and effectiveness. The polyherbal cream that was created had favorable physical and chemical characteristics, such as a pH that was appropriate for skin application, ideal viscosity, and good spreadability. With inhibitory zones comparable to those of conventional antifungal drugs, the cream showed strong antifungal efficacy against a variety of pathogenic fungal species. In addition, the cream exhibited no symptoms of skin irritation or unfavorable reactions in animal models, suggesting that it is safe for topical application.