The potential of tannins from medicinal plants as anti-cancer agents
Tanmay Jit, Saumendu Deb Roy, Dibyendu Shil, Jashabir Chakraborty, Amrit Paul, Sarbani Roy and Didhiti De
Herbal extracts or natural substances derived from plants have long been used as an alternative to pharmaceuticals in the prevention or treatment of various ailments, including cancer. Numerous investigations with plant chemicals sought to identify molecules that selectively cytotoxically affected aberrant cells. Among these are phenolic chemicals, which are significant secondary metabolites found in plants. This study surveys the research over the last five years regarding the potential anticancer effects of tannins derived from medicinal plants. To identify the most important components or plants with anticancer potential, the cytostatic/antitumor activities of the individual chemicals recovered from plants and/or of the polyphenolic extracts of the plants are taken into consideration. The most significant findings about the prevention of cancer using these substances and their derivatives and therapy, the significance of their molecular structure, there in vivo and in vitro mechanisms of action, and some elements of their bioavailability are covered. In this study, we discussed the anticancer properties of some plants with high tannin content.
Tanmay Jit, Saumendu Deb Roy, Dibyendu Shil, Jashabir Chakraborty, Amrit Paul, Sarbani Roy, Didhiti De. The potential of tannins from medicinal plants as anti-cancer agents. J Med Plants Stud 2024;12(4):414-423.