Herbal transdermal patch for wound healing: Formulation and in-vitro evaluation

Harshavardhan Gowda M; Lalitha C; Niharika CP; Preethi GB

doi:10.22271/plants.2025.v13.i2b.1815

**Herbal transdermal patch for wound healing: Formulation and in-vitro evaluation**

author(s)
Harshavardhan Gowda M, Lalitha C, Niharika CP and Preethi GB

abstract
Background: The biological process of wound healing is complex that includes tissue regeneration, inflammation and repair and treating it with ointments and dressings, often present challenges related to drug absorption, frequent application and patient discomfort. Transdermal patches have become an innovative drug delivery system to overcome these limitations, in matrix dispersion transdermal patch incorporates the drug into a polymer-solvent mixture, which, after solvent evaporation, forms a uniform drug-polymer matrix.

Materials and Methods: The goal of the project was to develop matrix dispersion system transdermal patch containing blend of natural wound healing agents such as aloe vera and turmeric using a combination of biocompatible polymers. Herbal transdermal patch was formulated using HPMC E15 as polymers with polyvinyl alcohol as plasticizer and polyethylene glycol as permeation enhancer.

Results: The transdermal patch underwent in-vitro evaluation that includes measurements of its thickness, folding endurance, weight uniformity, percentage of moisture content, pH and estimated curcumin content. Among these nine patches, formulation 6 demonstrated the best properties of the transdermal patch.

Conclusion: The results obtained from the study, demonstrated that a transdermal patch containing a combination of turmeric and aloe vera can be effectively made with HPMC E15, polyvinyl alcohol and polyethylene glycol.

doi
https://doi.org/10.22271/plants.2025.v13.i2b.1815

Pages : 144-148 | 130 Views | 53 Downloads

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How to cite this article:

Harshavardhan Gowda M, Lalitha C, Niharika CP, Preethi GB. Herbal transdermal patch for wound healing: Formulation and in-vitro evaluation. J Med Plants Stud 2025;13(2):144-148. DOI: 10.22271/plants.2025.v13.i2b.1815

2025, Vol. 13, Issue 2, Part B

**Herbal transdermal patch for wound healing: Formulation and in-vitro evaluation**

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