2025, Vol. 13, Issue 4, Part A

author(s)
Kinjal Boda, Rina Vasiyani, Kalpna Rakholiya, Trupesh Pethani and Mital J Kaneria

abstract
The development of sustainable method for nanoparticle synthesis has garnered significant interest in recent years. In the present study, biogenic fabrication of copper oxide (CuO) nanoparticles using extracts from selected medicinal plants as reducing and stabilizing agents. Antibacterial activity was examined using the agar well diffusion method, revealing significant inhibition zones, particularly against Gram-negative bacteria. Additionally, the antioxidant efficacy of the nanoparticles was assessed via DPPH free radical scavenging assay and ABTS cation radical scavenging, demonstrating remarkable concentration-dependent antioxidant activity. The synthesized nanoparticles were characterized using UV-Vis spectroscopy and zeta potential analysis. The findings highlight the potential of plant-mediated CuO nanoparticles as effective agents in biomedical applications due to their notable antibacterial and antioxidant properties.